Defender Tivonge Rushesha, winger Luke Motruk and striker Bradley Gibbings are part of the 16-man squad to face Dutch giants Ajax and Qatari development outfit Aspire Academy in challenging conditions.
Meanwhile, academy players Will Richard and Josh Thomas have also been called up to a Wales development squad for games in France this week.
Head of youth development Jon Grey praised the young players for their achievement.
"This is a fantastic opportunity for these young players to further their development with their national side," he said.
"Including Will (Richard) and Josh (Thomas), our academy has five players representing Wales at this level.
"Their call ups are testament to the hard work they continue to put in at the academy on a daily basis. It will give them a good insight into how the group will look to play going into their upcoming Victory Shield campaign."
The group will travel to the Middle East at the end of the month before playing the games in Doha over a five-day period.
Wales U15s squad: David Robson (Hearts), Cian Tyler (Coventry City), Ollie James-Denham (Manchester United), Jamie Taylor (Bristol City), Corey Glaves (Sheffield Wednesday), Tivonge Rushesha (Swansea City), Vinnie Dwyer (Wolverhampton Wanderers), Eli King (Cardiff City), Dan Malone (Stoke City), Chem Campbell (Wolverhampton Wanderers), Callum King-Harmes (Wolverhampton Wanderers) Owen Beck (Liverpool), Luke Rees (Hull City), Luke Motruk (Swansea City), Bradley Gibbings (Swansea City), Cavan Williams (Cardiff City).